Skip to main content

A Case of Persistent Hypokalaemia Leading to a Diagnosis of Carcinoid Lung Cancer with Positive Markers for Both Cushings and Carcinoid Syndrome

 Case Report

Volume 3, Issue 9 (September Issue) 

A Case of Persistent Hypokalaemia Leading to a Diagnosis of Carcinoid Lung Cancer with Positive Markers for Both Cushings and Carcinoid Syndrome

Benjamin Woolner1* and Ali Naqvi2

1Salisbury NHS Foundation Trust, United Kingdom

2Isle of Wight NHS Trust, United Kingdom

*Corresponding author: Benjamin Woolner, Salisbury NHS Foundation Trust, United Kingdom. E-mail: benjamin.woolner1@nhs.net

Received: October 28, 2021; Accepted: November 04, 2021; Published: November 15, 2021

Citation: Woolner B, Naqvi A, et al. A Case of Persistent Hypokalaemia Leading to a Diagnosis of Carcinoid Lung Cancer with Positive Markers for Both Cushing’s and Carcinoid Syndrome. Clin Image Case Rep J. 2021; 3(9): 190.

https://www.literaturepublishers.org

Abstract

An 81-years-old gentleman presented with a 2-week history of reduced appetite, lethargy and 2-3 kg weight loss over the previous one month. Routine investigations identified a potassium of 2.2 mmol/L. He was admitted for IV potassium replacement. His repeat potassium level after 3 days, was less than 2.9 mmol/L. His admission chest radiograph showed a suspicious lung lesion. A CT chest was arranged and revealed a left lower lobe lesion, consistent with a new malignancy, suspicious of a small cell lung cancer. Further biochemical and hormonal assays increased suspicions of an ACTH secreting carcinoid tumour. A PET scan, identified increased uptake of FDG in the lung lesion. Tumour histology was positive for ACTH, synaptophysin, chromogranin A and CD56 secretion. Proliferation index assessed with Ki67 was less than 1%. Chromogranin A was elevated, and Urine 5-HIAA testing was positive. A 24-hour free cortisol excretion test was elevated at 213 mmol/L. He was not a surgical candidate. Subsequently, he functionally deteriorated and was referred to the palliative team.

Keywords: Hypokalaemia; Carcinoid lung cancer; Cushing’s syndrome; Carcinoid syndrome

https://www.literaturepublishers.org/archive/A-Case-of-Persistent-Hypokalaemia-Leading-to-a-Diagnosis-of-Carcinoid-Lung-Cancer-with-Positive-Markers-for-Both-Cushings-and-Carcinoid-Syndrome.html

Labels:

Comments

Post a Comment

Popular posts from this blog

Recurrent Phytobezoar Presenting with Small Bowel Obstruction

Recurrent Phytobezoar Presenting with Small Bowel Obstruction *Corresponding author: Louise Dunphy, Department of Surgery, Wexham Park Hospital, Slough, UK, E-mail: Louise.Dunphy@doctors.org.uk Citation: Louise Dunphy, Syed Hussain Abbas and Stephen Baxter, et al. Recurrent Phytobezoar Presenting with Small Bowel Obstruction. Clin Image Case Rep J. 2019; 1(1): 105. Abstract  Small bowel obstruction is a common presentation to the emergency department, with causes including adhesions, hernia, malignancy, volvulus or complications of inflammatory bowel disease such as a stricture in Crohn’s disease. Indeed, it accounts for 20% of hospital admissions annually. Phytobezoars are a concentration of poorly digested fruit such as orange pith or pulp and vegetable fibres found in the alimentary tract in patients with a history of previous surgery or persimmon in patients without [1]. Small bowel phytobezoars are rare and are almost always obstructive. They pose a diagnostic a...
Post a Comment
Read more

Exporter of Reprints (Printed Material)

  What is Reprints? Reprints generally refer to copies of a previously published work. The meaning can vary slightly depending on the context: In Publishing (Books, Journals, Articles): • Reprints are additional printed copies of an article or book that has already been published. • Authors often request reprints of their scientific or medical journal articles to distribute to colleagues, conferences, or patients. • Book reprints are new print runs of a previously released edition, often without changes. Example • A doctor publishes a case report in a journal and requests 500 reprints to distribute at a medical conference. • A publisher prints a second batch of an already released novel — that’s a reprint. Use of Reprints Published article hard copy and reprints may be used to display the potential of the article at interviews, conferences, distribution to colleagues, seminars and other promotional activities, etc. Exporter of Reprints (Printed Material) We are an ex...
Post a Comment
Read more

Clinical Images and Case Reports Journal

  Clinical Images and Case Reports Journal (CICRJ)  is a peer-reviewed high impact factor PMC indexed medical journal established Internationally which provides a platform to publish Clinical Images, Medical Case Reports, Clinical Case Reports, Case Series (series of 2 to 6 cases), Research, Reviews and Clinical Videos in Medicine. Journal encourages publication of medical case reports for physicians and medical aspirants to share different results in the form of clinical image articles and medical case reports, which have been encountered in different medical sub-specialties or cases which leads to a higher understanding of the medical conditions, medicines, diagnosis and management. Medical case reports journal presents different possibilities to enhance worldwide health outcomes. Clinical case reports journal publishes methods of diagnosis, treatment, and prevention of diseases. Clinical imaging journal will consider any original case report in medicine that...
Post a Comment
Read more